Statins Slash GLP-1 Levels: Human Controlled Trial
Nick Norwitz, MD, PhD — Statins Slash GLP-1 Levels: Human Controlled Trial
Channel: Nick Norwitz MD PhD · Our label: Physician-researcher educator · Source: youtube.com/watch?v=6NomrgjK1yQ
What this video covers
But the paper I just read, it also annoyed me a lot. It explored how statins, the most profitable drugs in history with annual sales exceeding 20 billion globally, contribute to insulin resistance, increase type 2 diabetes risk, and and significantly lower GLP-1 levels in humans. Now, it’s relatively well known that statins cause insulin resistance and can increase the risk of diabetes. But the direct negative impact on GLP-1 levels, which I’m going to show you, is substantial.
Summary drawn from this video’s own transcript (banked in our research library, pulled 2026-11-07). Claims below are the speaker’s — attributed, not endorsed. This site publishes no dosing, protocol, or sourcing information.
Key points, in the speaker’s own framing
- It explored how statins, the most profitable drugs in history with annual sales exceeding 20 billion globally, contribute to insulin resistance, increase type 2 diabetes risk, and and significantly lower GLP-1 levels in humans.
- Now, it’s relatively well known that statins cause insulin resistance and can increase the risk of diabetes.
- And at the same time, the statins caused a sharp drop in GLP-1 levels by nearly 50% by the end of the four-month trial with a continued downtrend that’s clearly visible.
- So effectively, an Amazon supplement can increase levels of this bile acid, which was found in this human study to boost GLP-1 levels and offset some of the negative effects of statins on insulin resistance.
- Clinicians deserve systems that help support their pursuit of true health, not just protocols and compliance.
- And if you’re a clinician or a student doctor, read the study, reflect on your practice and education, talk to colleagues, raise the issue in your next journal club or case conference.
Read next
Educational information only — not medical advice. Peptides discussed on this page include substances that are not FDA-approved.